Proposition 8 was a California ballot proposition that changed the state Constitution to restrict the definition of marriage to a union between a man and a woman and eliminated the right of same-sex couples to marry. (src) A lot of prominent people opposed the proposition in many ways, however I found this one unique: Funny Or Die's Prop 8 - The Musical, starring - among others - Jack Black, John C. Reilly, Neil Patrick Harris.

'Jesus Christ!'
'Hey, how's it goin''